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  • Acetylcholinesterase Antibodies

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Acetylcholinesterase Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers

Cite Acetylcholinesterase Polyclonal Antibody

  • Antibody Testing Data (1)
Acetylcholinesterase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Acetylcholinesterase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Acetylcholinesterase Antibody (BS-2511R) in IHC (P)

Formalin-fixed and paraffin embedded rat heart labeled with Anti- ACHE/Acetylcholinesterase Polyclonal Antibody, Unconjugated (bs-2511R) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3) used at 1:200 dilution for 40 minutes at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Acetylcholinesterase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Acetylcholinesterase Polyclonal Antibody

Product Details

BS-2511R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human AchE, amino acids 521-614.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Acetylcholinesterase; acetylcholinesterase (Yt blood group); AChE; apoptosis-related acetylcholinesterase; EC 3.1.1.7; glycolipid-anchored form of acetylcholinesterase; OTTHUMP00000211349; OTTHUMP00000211356; Yt blood group

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Gene Aliases: ACEE; ACHE; ARACHE; N-ACHE; YT

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UniProt ID: (Human) P22303, (Mouse) P21836, (Rat) P37136

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Entrez Gene ID: (Human) 43, (Mouse) 11423, (Rat) 83817

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Function(s)
beta-amyloid binding acetylcholinesterase activity cholinesterase activity protein binding collagen binding hydrolase activity serine hydrolase activity acetylcholine binding protein homodimerization activity laminin binding protein self-association choline binding carboxylic ester hydrolase activity
Process(es)
regulation of receptor recycling acetylcholine catabolic process cell adhesion synapse assembly acetylcholine metabolic process choline metabolic process receptor internalization neurotransmitter catabolic process neurotransmitter receptor biosynthetic process positive regulation of axonogenesis positive regulation of dendrite morphogenesis protein tetramerization retina development in camera-type eye neuron death osteoblast development acetylcholine catabolic process in synaptic cleft DNA replication phosphatidylcholine biosynthetic process nervous system development muscle organ development cell proliferation response to wounding negative regulation of synaptic transmission, cholinergic neurotransmitter biosynthetic process amyloid precursor protein metabolic process positive regulation of protein secretion
It has to be done as per old AB suggested Products section.
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