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Invitrogen
Acetyl-CoA Carboxylase Polyclonal Antibody
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FIGURE: 1 / 6
Acetyl-CoA Carboxylase Antibody (PA5-90578) in ICC/IF
Product Details
PA5-90578
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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RRID
Product Specific Information
Positive Samples: HeLa, C2C12, C6; Cellular Location: Cytoplasm
Immunogen sequence: NNKDLAEWLE KQLTEEDGVH SVIEENIKCI SRDYVLKQIR SLVQANPEVA MDSIIHMTQH ISPTQRAEVI RILSTMDSPS T
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: acaca; ACC-alpha; ACC1; Acetyl-CoA carboxylase 1; Acetyl-CoA carboxylase 265; Acetyl-Coenzyme A carboxylase alpha; EC 6.3.4.14; EC 6.4.1.2
Gene Aliases: A530025K05Rik; ACAC; ACACA; ACACAD; ACC; ACC1; ACCA; Gm738
UniProt ID: (Human) Q13085, (Mouse) Q5SWU9, (Rat) P11497
Entrez Gene ID: (Human) 31, (Mouse) 107476, (Rat) 60581
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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