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  • Primary Antibodies ›
  • ASM Antibodies

Invitrogen

ASM Polyclonal Antibody

View all (15) ASM antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite ASM Polyclonal Antibody

  • Antibody Testing Data (1)
ASM Antibody in Western Blot (WB)
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ASM Antibody in Western Blot (WB)
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ASM Antibody (PA1-12756) in WB

Western blot analysis of ASM using a polyclonal antibody (Product # PA1-12756). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ASM Antibody in Western Blot (WB)

Product Details

PA1-12756

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide derived from human acid sphingomyelinase.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

PBS

Contains

0.08% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2193395

Target Information

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Three transcript variants encoding two different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Acid sphingomyelinase; aSMase; Sphingomyelin phosphodiesterase; sphingomyelin phosphodiesterase 1, acid lysosomal

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Gene Aliases: ASM; ASMASE; NPD; SMPD1

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UniProt ID: (Human) P17405

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Entrez Gene ID: (Human) 6609

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Function(s)
sphingomyelin phosphodiesterase activity protein binding zinc ion binding hydrolase activity, acting on glycosyl bonds acid sphingomyelin phosphodiesterase activity
Process(es)
sphingomyelin metabolic process sphingomyelin catabolic process glycosphingolipid metabolic process signal transduction nervous system development termination of signal transduction positive regulation of protein dephosphorylation response to cocaine response to drug positive regulation of apoptotic process negative regulation of MAP kinase activity ceramide biosynthetic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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