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  • Primary Antibodies ›
  • ASIC3 Antibodies

Osenses

ASIC3 Polyclonal Antibody

1 Reference
View all (16) ASIC3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ASIC3 Polyclonal Antibody

  • Antibody Testing Data (10)
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 10

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ASIC3 Antibody (OSR00096W-100UL) in IHC (P)

IHC-P on paraffin sections of human brain. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Primary antibody: dilution 1:1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ASIC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

OSR00096W-100UL

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000
-

Miscellaneous PubMed (MISC)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from aa region 450-490 of human ASIC3 conjugated to blue carrier protein was used as the antigen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: ASIC3.

Target Information

ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: acid sensing (proton gated) ion channel 3; acid sensing ion channel 3; acid-sensing (proton-gated) ion channel 3; Acid-sensing ion channel 3; Amiloride-sensitive cation channel 3; amiloride-sensitive cation channel 3, testis; ASIC3; hASIC3; hTNaC1; modulatory subunit of ASIC2a; Neuronal amiloride-sensitive cation channel 3; proton-gated cation channel subunit; Testis sodium channel 1

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Gene Aliases: ACCN3; ASIC3; DRASIC; SLNAC1; TNAC1

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UniProt ID: (Human) Q9UHC3

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Entrez Gene ID: (Human) 9311

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Function(s)
cation channel activity sodium channel activity PDZ domain binding enterobactin transporter activity acid-sensing ion channel activity
Process(es)
transport signal transduction sensory perception response to heat response to acidic pH ion transmembrane transport sodium ion transmembrane transport enterobactin transport sensory perception of sour taste detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain detection of chemical stimulus involved in sensory perception of pain
It has to be done as per old AB suggested Products section.
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