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  • ARRDC3 Antibodies

Invitrogen

ARRDC3 Polyclonal Antibody

View all (4) ARRDC3 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite ARRDC3 Polyclonal Antibody

  • Antibody Testing Data (1)
ARRDC3 Antibody in Western Blot (WB)
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ARRDC3 Antibody in Western Blot (WB)
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ARRDC3 Antibody (PA5-109414) in WB

Western blot analysis of ARRDC3 in extracts of Rat liver. Samples were incubated with ARRDC3 Polyclonal antibody (Product # PA5-109414) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ARRDC3 Antibody in Western Blot (WB)
ARRDC3 Polyclonal Antibody

Product Details

PA5-109414

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ARRDC3 (NP_065852.1).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.73 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854825

Product Specific Information

Immunogen sequence: MVLGKVKSLT ISFDCLNDSN VPVYSSGDTV SGRVNLEVTG EIRVKSLKIH ARGHAKVRWT ESRNAGSNTA YTQNYTEEVE YFNHKDILIG HERDDDNSEE GFHTIHSGRH EYAFSFELPQ TPLATSFEGR HGSVRYWVKA ELHRPWLLPV KLKKEFTVFE HIDINTPSLL SPQAGTKEKT LCCWFCTSGP ISLSAKIERK GYTPGESIQI FAEIENCSSR MVVPKAAIYQ TQAFYAKGKM KEVKQLVANL RGESLSSGKT ETWNGKLLKI

Target Information

Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis of activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Arrestin domain-containing protein 3; Liver regeneration-related protein LRRG00048

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Gene Aliases: Arrdc3; LRRGT00048

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UniProt ID: (Rat) Q6TXF1

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Entrez Gene ID: (Rat) 309945

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Function(s)
beta-3 adrenergic receptor binding
Process(es)
temperature homeostasis negative regulation of heat generation skin development negative regulation of multicellular organismal metabolic process positive regulation of ubiquitin-protein transferase activity fat pad development positive regulation of adrenergic receptor signaling pathway negative regulation of locomotion involved in locomotory behavior
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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