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ARHGDIB Monoclonal Antibody (3E7B7)

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Datasheet
Protocols
Questions & Answers

Cite ARHGDIB Monoclonal Antibody (3E7B7)

  • Antibody Testing Data (7)
ARHGDIB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ARHGDIB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 7

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ARHGDIB Antibody (66054-1-IG) in IHC (P)

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 66054-1-IG (ARHGDIB antibody) at dilution of 1:10000 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ARHGDIB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ARHGDIB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ARHGDIB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ARHGDIB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ARHGDIB Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
ARHGDIB Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
ARHGDIB Antibody in Western Blot (WB)
ARHGDIB Monoclonal Antibody (3E7B7)

Product Details

66054-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:10,000-1:50,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:5,000-1:10,000
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:10,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

3E7B7

Immunogen

ARHGDIB Fusion Protein Ag9091 (1-201 aa encoded by BC009200)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated
  • CoraLite 594
  • Request custom conjugation

Form

Liquid

Concentration

1.01 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MTEKAPEPH VEEDDDDELD SKLNYKPPPQ KSLKELQEMD KDDESLIKYK KTLLGDGPVV TDPKAPNVVV TRLTLVCESA PGPITMDLTG DLEALKKETI VLKEGSEYRV KIHFKVNRDI VSGLKYVQHT YRTGVKVDKA TFMVGSYGPR PEEYEFLTPV EEAPKGMLAR GTYHNKSFFT DDDKQDHLSW EWNLSIKKEW TE (1-201 aa encoded by BC009200)

Target Information

Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: D4; d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta

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Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2

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UniProt ID: (Human) P52566, (Mouse) Q61599

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Entrez Gene ID: (Human) 397, (Rat) 362456, (Mouse) 11857

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Function(s)
GTPase activity Rho GDP-dissociation inhibitor activity GTPase activator activity protein binding Rac GTPase binding
Process(es)
regulation of catalytic activity cellular response to redox state metabolic process negative regulation of trophoblast cell migration movement of cell or subcellular component negative regulation of cell adhesion multicellular organism development regulation of Rho protein signal transduction positive regulation of GTPase activity regulation of small GTPase mediated signal transduction regulation of actin cytoskeleton reorganization
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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