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ARHGDIB Polyclonal Antibody, MaxPab™

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Datasheet
Protocols
Questions & Answers

Cite ARHGDIB Polyclonal Antibody, MaxPab™

  • Antibody Testing Data (3)
ARHGDIB Antibody in Western Blot (WB)
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ARHGDIB Antibody in Western Blot (WB)
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ARHGDIB Antibody (H00000397-D01P) in WB

Western Blot analysis of ARHGDIB expression in transfected 293T cell line (H00000397-T01) by ARHGDIB MaxPab polyclonal antibody.

Lane 1: ARHGDIB transfected lysate(23.00 KDa).
Lane 2: Non-transfected lysate.
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ARHGDIB Antibody in Western Blot (WB)
ARHGDIB Antibody in Western Blot (WB)
ARHGDIB Antibody in Western Blot (WB)
ARHGDIB Polyclonal Antibody, MaxPab™

Product Details

H00000397-D01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ARHGDIB (NP_001166.3, 1 a.a. approximately 201 a.a) full-length human protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK TLLGDGPVVT DPKAPNVVVT RLTLVCESAP GPITMDLTGD LEALKKETIV LKEGSEYRVK IHFKVNRDIV SGLKYVQHTY RTGVKVDKAT FMVGSYGPRP EEYEFLTPVE EAPKGMLARG TYHNKSFFTD DDKQDHLSWE WNLSIKKEWT E

Target Information

Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: D4; d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta

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Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2

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UniProt ID: (Human) P52566, (Mouse) Q61599

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Entrez Gene ID: (Human) 397, (Mouse) 11857

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Function(s)
GTPase activity Rho GDP-dissociation inhibitor activity GTPase activator activity protein binding Rac GTPase binding
Process(es)
metabolic process negative regulation of trophoblast cell migration movement of cell or subcellular component negative regulation of cell adhesion multicellular organism development regulation of Rho protein signal transduction positive regulation of GTPase activity regulation of small GTPase mediated signal transduction cellular response to redox state regulation of actin cytoskeleton reorganization
It has to be done as per old AB suggested Products section.
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