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  • ApoC3 Antibodies

Bioss

APOC3 Polyclonal Antibody

View all (22) ApoC3 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite APOC3 Polyclonal Antibody

APOC3 Polyclonal Antibody

Product Details

BS-5037R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from rat Apolipoprotein CIII, amino acids 41-80.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Apo-CIII; Apolipoprotein; apolipoprotein C-3; Apolipoprotein C-III; Apolipoprotein C3; MGC150353

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Gene Aliases: apo-CIII; ApoC-III; Apoc3

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UniProt ID: (Mouse) P33622

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Entrez Gene ID: (Mouse) 11814, (Rat) 24207

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Function(s)
lipid binding lipid transporter activity phospholipid binding enzyme regulator activity lipase inhibitor activity high-density lipoprotein particle receptor binding
Process(es)
lipid metabolic process triglyceride metabolic process triglyceride mobilization transport lipid transport cholesterol metabolic process lipid catabolic process triglyceride catabolic process lipoprotein metabolic process lipoprotein transport response to peptide hormone cellular response to glucose stimulus inflammatory response G-protein coupled receptor signaling pathway response to nutrient negative regulation of triglyceride catabolic process negative regulation of very-low-density lipoprotein particle remodeling negative regulation of very-low-density lipoprotein particle clearance negative regulation of high-density lipoprotein particle clearance negative regulation of low-density lipoprotein particle clearance regulation of Cdc42 protein signal transduction cholesterol efflux phospholipid efflux high-density lipoprotein particle remodeling chylomicron remnant clearance response to drug cholesterol homeostasis negative regulation of fatty acid biosynthetic process negative regulation of lipid metabolic process negative regulation of receptor-mediated endocytosis negative regulation of lipid catabolic process negative regulation of lipoprotein lipase activity negative regulation of cholesterol import triglyceride homeostasis
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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