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  • Primary Antibodies ›
  • APOB48R Antibodies

OriGene

APOBR Monoclonal Antibody (OTI1B1), TrueMAB™

View all (25) APOB48R antibodies

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Cite APOBR Monoclonal Antibody (OTI1B1), TrueMAB™

  • Antibody Testing Data (7)
APOBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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APOBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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APOBR Antibody (CF807064) in IHC (P)

Immunohistochemical staining of paraffin-embedded human endometrium tissue within the normal limits using anti-APOBR mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA807064) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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APOBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
APOBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
APOBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
APOBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
APOBR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
APOBR Antibody in Western Blot (WB)
APOBR Antibody in Western Blot (WB)
APOBR Monoclonal Antibody (OTI1B1), TrueMAB™

Product Details

CF807064

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1B1

Immunogen

Human recombinant protein fragment corresponding to amino acids 780-1088 of human APOBR produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: apoB-48R; Apolipoprotein B receptor; Apolipoprotein B-100 receptor; Apolipoprotein B-48 receptor; apolipoprotein B100 receptor; Apolipoprotein B48 receptor

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Gene Aliases: APOB100R; APOB48R; APOBR

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UniProt ID: (Human) Q0VD83

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Entrez Gene ID: (Human) 55911

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Function(s)
very-low-density lipoprotein particle receptor activity
Process(es)
triglyceride metabolic process lipid transport receptor-mediated endocytosis cholesterol metabolic process
It has to be done as per old AB suggested Products section.
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