Invitrogen

APOA4 Polyclonal Antibody

View all (36) Apolipoprotein A4 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
APOA4 Polyclonal Antibody

Product Details

PA5-118955

Applications
Tested Dilution
Publications

Western Blot (WB)

0.01-3 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

5-30 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein Apolipoprotein A4. The antigen corresponds to amino acid range Lys209-Ser396 of the target protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2903455

Target Information

Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is an O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but evidence from several in vitro studies indicate that this apolipoprotein is involved in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Apo-AIV; apoA-IV; Apolipoprotein A-IV; Apolipoprotein A4; MGC142154; MGC142156

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Gene Aliases: APOA4

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UniProt ID: (Human) P06727

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Entrez Gene ID: (Human) 337

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Function(s)
lipid transporter activity copper ion binding protein binding lipid binding cholesterol binding antioxidant activity cholesterol transporter activity phosphatidylcholine binding protein homodimerization activity phosphatidylcholine-sterol O-acyltransferase activator activity
Process(es)
retinoid metabolic process innate immune response in mucosa cholesterol biosynthetic process lipid transport response to lipid hydroperoxide leukocyte cell-cell adhesion cholesterol metabolic process positive regulation of cholesterol esterification positive regulation of triglyceride catabolic process removal of superoxide radicals regulation of intestinal cholesterol absorption neuron projection regeneration regulation of cholesterol transport cholesterol efflux phospholipid efflux chylomicron remodeling very-low-density lipoprotein particle remodeling high-density lipoprotein particle remodeling chylomicron assembly high-density lipoprotein particle assembly negative regulation of plasma lipoprotein particle oxidation response to stilbenoid lipoprotein metabolic process lipoprotein biosynthetic process cholesterol homeostasis hydrogen peroxide catabolic process reverse cholesterol transport multicellular organism lipid catabolic process cellular protein metabolic process positive regulation of fatty acid biosynthetic process phosphatidylcholine metabolic process positive regulation of lipoprotein lipase activity lipid homeostasis protein-lipid complex assembly triglyceride homeostasis
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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