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Proteintech

ANKRD1 Polyclonal Antibody

13 References
View all (13) CARP antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ANKRD1 Polyclonal Antibody

  • Antibody Testing Data (2)
ANKRD1 Antibody in Western Blot (WB)
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ANKRD1 Antibody in Western Blot (WB)
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FIGURE: 1 / 2

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ANKRD1 Antibody (11427-1-AP) in WB

Mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11427-1-AP (ANKRD1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ANKRD1 Antibody in Western Blot (WB)
ANKRD1 Antibody in Western Blot (WB)
ANKRD1 Polyclonal Antibody

Product Details

11427-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:4,000
View 10 publications 10 publications

Immunocytochemistry (ICC/IF)

Assay-dependent
View 3 publications 3 publications
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ANKRD1 Fusion Protein Ag1970 (1-319 aa encoded by BC018667)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This is a rabbit polyclonal antibody produced by the full-length ANKRD1 of human origin.

Immunogen sequence: MMVLKVEEL VTGKKNGNGE AGEFLPEDFR DGEYEAAVTL EKQEDLKTLL AHPVTLGEQQ WKSEKQREAE LKKKKLEQRS KLENLEDLEI IIQLKKRKKY RKTKVPVVKE PEPEIITEPV DVPTFLKAAL ENKLPVVEKF LSDKNNPDVC DEYKRTALHR ACLEGHLAIV EKLMEAGAQI EFRDMLESTA IHWASRGGNL DVLKLLLNKG AKISARDKLL STALHVAVRT GHYECAEHLI ACEADLNAKD REGDTPLHDA VRLNRYKMIR LLIMYGADLN IKNCAGKTPM DLVLHWQNGT KAIFDSLREN SYKTSRIATF (1-319 aa encoded by BC018667)

Target Information

The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain-containing protein 1; ankyrin-like repeat protein; Cardiac adriamycin-responsive protein; Cardiac ankyrin repeat protein; cardiac responsive adriamycin protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; liver ankyrin repeat domain 1; muscle ankyrin repeat protein

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Gene Aliases: ALRP; ANKRD1; bA320F15.2; C-193; C193; CARP; Crap; CVARP; HA1A2; MARP; MARP1; MCARP

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UniProt ID: (Human) Q15327, (Mouse) Q9CR42, (Rat) Q8R560

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Entrez Gene ID: (Human) 27063, (Mouse) 107765, (Rat) 27064

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Function(s)
RNA polymerase II transcription factor binding RNA polymerase II transcription coactivator activity p53 binding DNA binding transcription corepressor activity protein binding titin binding histone deacetylase binding R-SMAD binding transcription factor binding transcription cofactor activity
Process(es)
negative regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter positive regulation of neuron projection development cellular response to drug skeletal muscle cell differentiation response to muscle stretch positive regulation of apoptotic process positive regulation of DNA damage response, signal transduction by p53 class mediator positive regulation of transcription from RNA polymerase II promoter positive regulation of protein secretion cardiac muscle tissue morphogenesis cellular response to lipopolysaccharide cellular response to mechanical stimulus cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to transforming growth factor beta stimulus negative regulation of nucleic acid-templated transcription negative regulation of DNA biosynthetic process muscle cell differentiation negative regulation of transcription, DNA-templated cellular response to organic cyclic compound cellular response to hypoxia sarcomere organization
It has to be done as per old AB suggested Products section.
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