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Invitrogen
ANGPTL7 Polyclonal Antibody
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FIGURE: 1 / 4
ANGPTL7 Antibody (PA5-106604) in ICC/IF
Product Details
PA5-106604
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
Storage buffer
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Product Specific Information
Antibody detects endogenous levels of total ANGPTL7.
Target Information
Angptl7 (angiopoietin-like 7), alternately known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein that is expressed specifically in the stromal layer of cornea. Angptl7 forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression. The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: angiopoietin-like 7; Angiopoietin-like factor; angiopoietin-like factor (CDT6); Angiopoietin-like protein 7; Angiopoietin-related protein 7; Cornea-derived transcript 6 protein
Gene Aliases: ANGPTL7; AngX; CDT6; dJ647M16.1; UNQ313/PRO356
UniProt ID: (Human) O43827, (Mouse) Q8R1Q3
Entrez Gene ID: (Human) 10218, (Mouse) 654812
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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