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  • AMHR2 Antibodies

Invitrogen

AMHR2 Recombinant Rabbit Monoclonal Antibody (7R5V8)

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Datasheet
Protocols
Questions & Answers

Cite AMHR2 Recombinant Rabbit Monoclonal Antibody (7R5V8)

  • Antibody Testing Data (1)
AMHR2 Antibody in Western Blot (WB)
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AMHR2 Antibody in Western Blot (WB)
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AMHR2 Antibody (MA5-55385) in WB

Western Blot analysis of various lysates using AMHR2 Recombinant Monoclonal Antibody (Product # MA5-55385) at 1:2,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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AMHR2 Antibody in Western Blot (WB)
AMHR2 Recombinant Rabbit Monoclonal Antibody (7R5V8)

Product Details

MA5-55385

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7R5V8

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 18-144 of human AMHR2.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.84 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

RRID

AB_3667626

Product Specific Information

Immunogen Sequence: PPNRRTCVFF EAPGVRGSTK TLGELLDTGT ELPRAIRCLY SRCCFGIWNL TQDRAQVEMQ GCRDSDEPGC ESLHCDPSPR AHPSPGSTLF TCSCGTDFCN ANYSHLPPPG SPGTPGSQGP QAAPGES

Target Information

The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AMH type II receptor; Anti-Muellerian hormone type II receptor; Anti-Muellerian hormone type-2 receptor; anti-Mullerian hormone receptor type II; anti-Mullerian hormone receptor, type II; anti-Mullerian hormone type 2 receptor delta 2; anti-Mullerian hormone type 2 receptor delta 9/10; MIS type II receptor; MISRII; Muellerian inhibiting substance type II receptor; Mullerian inhibiting substance type II receptor

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Gene Aliases: AMHR; AMHR2; Misiir; MISR2; MISRII; MRII

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UniProt ID: (Human) Q16671, (Mouse) Q8K592

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Entrez Gene ID: (Human) 269, (Mouse) 110542

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Function(s)
receptor signaling protein serine/threonine kinase activity receptor activity transforming growth factor beta receptor activity, type II protein binding ATP binding hormone binding metal ion binding anti-Mullerian hormone receptor activity nucleotide binding protein kinase activity protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity transforming growth factor beta-activated receptor activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups
Process(es)
protein phosphorylation signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway transforming growth factor beta receptor signaling pathway G-protein coupled receptor signaling pathway sex differentiation phosphorylation negative regulation of anti-Mullerian hormone signaling pathway anti-Mullerian hormone signaling pathway Mullerian duct regression male gonad development female gonad development signal transduction by protein phosphorylation
It has to be done as per old AB suggested Products section.
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