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  • ALOX5 Antibodies

OriGene

ALOX5 Monoclonal Antibody (OTI3F1), TrueMAB™

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Questions & Answers

Cite ALOX5 Monoclonal Antibody (OTI3F1), TrueMAB™

  • Antibody Testing Data (13)
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ALOX5 Antibody (TA807013) in IHC (P)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ALOX5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA807013)(1:150). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALOX5 Antibody in Western Blot (WB)
ALOX5 Monoclonal Antibody (OTI3F1), TrueMAB™

Product Details

TA807013

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OTI3F1

Immunogen

Human recombinant protein fragment corresponding to amino acids 18-364 of human ALOX5 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 5-LO; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; leukotriene A4 synthase; LOX-5; lox5; Polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3

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Gene Aliases: 5-LO; 5-LOX; 5LPG; ALOX5; LOG5

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UniProt ID: (Human) P09917

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Entrez Gene ID: (Human) 240

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Function(s)
arachidonate 5-lipoxygenase activity iron ion binding protein binding
Process(es)
acute inflammatory response leukotriene production involved in inflammatory response leukotriene metabolic process response to nutrient sensory perception of pain arachidonic acid metabolic process leukotriene biosynthetic process lipoxygenase pathway positive regulation of vasoconstriction response to hyperoxia oxidation-reduction process lipoxin metabolic process
It has to be done as per old AB suggested Products section.
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