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  • Primary Antibodies ›
  • ALDH1A2 Antibodies

Invitrogen

ALDH1A2 Polyclonal Antibody

View all (15) ALDH1A2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ALDH1A2 Polyclonal Antibody

  • Antibody Testing Data (4)
ALDH1A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ALDH1A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 4

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ALDH1A2 Antibody (PA5-117779) in IHC (P)

Immunohistochemical staining of human ALDH1A2 in human corpus uteri with ALDH1A2 Polyclonal Antibody (Product # PA5-117779, 1:100 dilution, formalin-fixed paraffin embedded sections). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ALDH1A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALDH1A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ALDH1A2 Antibody in Western Blot (WB)
ALDH1A2 Antibody in Immunoprecipitation (IP)

Product Details

PA5-117779

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunoprecipitation (IP)

1-5 µL/mg of lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived Human ALDH1A2 fragment

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7

Contains

0.03% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2902390

Target Information

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AL1A2; aldehyde dehydrogenase 1 family, member A2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; RALDH 2; RALDH(II); Retinal dehydrogenase 2; Retinaldehyde-specific dehydrogenase type 2

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Gene Aliases: ALDH1A2; RALDH(II); RALDH2; RALDH2-T

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UniProt ID: (Human) O94788

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Entrez Gene ID: (Human) 8854

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Function(s)
retinal dehydrogenase activity 3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD) activity retinal binding
Process(es)
blood vessel development kidney development liver development regulation of endothelial cell proliferation retinoic acid biosynthetic process heart morphogenesis vitamin A metabolic process midgut development positive regulation of cell proliferation negative regulation of cell proliferation determination of bilateral symmetry anterior/posterior pattern specification proximal/distal pattern formation positive regulation of gene expression neural crest cell development morphogenesis of embryonic epithelium neural tube development pituitary gland development neuron differentiation lung development hindbrain development pancreas development embryonic camera-type eye development response to estradiol response to vitamin A response to cytokine embryonic forelimb morphogenesis ureter maturation retinol metabolic process retinoic acid metabolic process retinal metabolic process 9-cis-retinoic acid biosynthetic process positive regulation of apoptotic process retinoic acid receptor signaling pathway embryonic digestive tract development cardiac muscle tissue development oxidation-reduction process face development cellular response to retinoic acid
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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