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Proteintech
AKR1C4 Polyclonal Antibody
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Product Details
18852-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: MDPKYQRVE LNDGHFMPVL GFGTYAPPEV PRNRAVEVTK LAIEAGFRHI DSAYLYNNEE QVGLAIRSKI ADGSVKREDI FYTSKLWCTF FQPQMVQPAL ESSLKKLQLD YVDLYLLHFP MALKPGETPL PKDENGKVIF DTVDLSATWE VMEKCKDAGL AKSIGVSNFN YRQLEMILNK PGLKYKPVCN QVECHPYLNQ SKLLDFCKSK DIVLVAHSAL GTQRHKLWVD PNSPVLLEDP VLCALAKKHK RTPALIALRY QLQRGVVVLA KSYNEQRIRE NIQVFEFQLT SEDMKVLDGL NRNYRYVVMD FLMDHPDYPF SDEY (1-323 aa encoded by BC020744)
Target Information
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 3-alpha-HSD1; 3-alpha-hydroxysteroid dehydrogenase type I; 3alpha-hydroxysteroid 3-dehydrogenase; Aldo-keto reductase family 1 member C4; CDR; Chlordecone reductase; chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4; DD-4; Dihydrodiol dehydrogenase 4; dihydrodiol dehydrogenase isozyme DD4; HAKRA; HGNC:387; MGC22581; type I 3-alpha-hydroxysteroid dehydrogenase
Gene Aliases: 3-alpha-HSD; AKR1C4; C11; CDR; CHDR; DD-4; DD4; HAKRA
UniProt ID: (Human) P17516
Entrez Gene ID: (Human) 1109
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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