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  • Primary Antibodies ›
  • ACTH Antibodies

Fabgennix

ACTH Polyclonal Antibody

View all (48) ACTH antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite ACTH Polyclonal Antibody

  • Antibody Testing Data (1)
ACTH Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ACTH Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 1

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ACTH Antibody (ACTH-101AP) in IHC (P)

Mouse Brain- ACTH; Primary Antibody: ACTH-101AP; 1:100 dilution in IHC Blocking Buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification. FFPE section. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ACTH Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTH Polyclonal Antibody

Product Details

ACTH-101AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:250
-

Immunocytochemistry (ICC/IF)

1:50-1:250
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:100-1:250
-

Dot blot (DB)

1:10,000
-

Immunomicroscopy (IM)

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to ACTH aa 138-176. Sequence:SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

ATCH (adrenocorticotropic hormone) is a hormone which plays a major role in stimulating the adrenal cortex. It is formed through cleavage of the polypeptide precursor proopiomelanocortin (POMC), which also results in several other cleavage products including MSH, ACTH, and beta endorphin. ATCH is secreted from the anterior pituitary in response to the corticotropin-releasing hormone from the hypothalamus. It stimulates the secretion of glucocorticoids like cortisol, but has little control over the stimulation of mineralocorticoids like aldosterone, which is another major hormone of the adrenal cortex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: adrenal corticotropic hormone; adrenocorticotropic hormone; adrenocorticotropin; alpha-melanocyte stimulating hormone; alpha-melanocyte-stimulating hormone; alpha-MSH; beta-endorphin; beta-LPH; beta-melanocyte-stimulating hormone; beta-MSH; corticotropin-like intermediary peptide; Corticotropin-lipotropin; gamma-LPH; gamma-MSH; lipotropin beta; lipotropin gamma; melanotropin alpha; melanotropin beta; melanotropin gamma; met-enkephalin; opiomelanocortin prepropeptide; OTTHUMP00000119991; OTTHUMP00000200964; POMC; Precursor of MSH; pro-ACTH-endorphin; Pro-opiomelanocortin; pro-opiomelanocortin-alpha; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); proopiomelanocortin preproprotein; proopiomelanocortin, beta (endorphin, beta); proopoimelanocortin, beta (endorphin, beta)

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Gene Aliases: ACTH; alpha-MSH; alphaMSH; BE; Beta-LPH; beta-MSH; CLIP; Gamma-LPH; gamma-MSH; LPH; MSH; NPP; POC; POMC; Pomc-1; Pomc1; Pomc2

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UniProt ID: (Human) P01189, (Mouse) P01193

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Entrez Gene ID: (Human) 5443, (Mouse) 18976, (Rat) 24664

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Function(s)
G-protein coupled receptor binding receptor binding hormone activity neuropeptide hormone activity type 3 melanocortin receptor binding type 4 melanocortin receptor binding type 1 melanocortin receptor binding molecular_function
Process(es)
generation of precursor metabolites and energy signal transduction neuropeptide signaling pathway cell-cell signaling regulation of blood pressure regulation of appetite negative regulation of tumor necrosis factor production cellular pigmentation glucose homeostasis positive regulation of transcription from RNA polymerase II promoter regulation of glycogen metabolic process regulation of corticosterone secretion feeding behavior peptide hormone processing
It has to be done as per old AB suggested Products section.
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