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  • ACTH Antibodies

NeoBiotechnologies

ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Monoclonal Antibody (r57)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Monoclonal Antibody (r57)

  • Antibody Testing Data (2)
ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Antibody (5443-MSM6-P0) in IHC (P)

Formalin-fixed, paraffin-embedded human pituitary gland stained with ACTH Recombinant Mouse Monoclonal Antibody (r57). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Antibody in SDS-PAGE (SDS-PAGE)
ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Monoclonal Antibody (r57)

Product Details

5443-MSM6-P0

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

r57

Immunogen

N-terminal fragment of human ACTH conjugated to KLH
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Wet ice

Target Information

ATCH (adrenocorticotropic hormone) is a hormone which plays a major role in stimulating the adrenal cortex. It is formed through cleavage of the polypeptide precursor proopiomelanocortin (POMC), which also results in several other cleavage products including MSH, ACTH, and beta endorphin. ATCH is secreted from the anterior pituitary in response to the corticotropin-releasing hormone from the hypothalamus. It stimulates the secretion of glucocorticoids like cortisol, but has little control over the stimulation of mineralocorticoids like aldosterone, which is another major hormone of the adrenal cortex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: adrenal corticotropic hormone; adrenocorticotropic hormone; adrenocorticotropin; alpha-melanocyte stimulating hormone; alpha-melanocyte-stimulating hormone; alpha-MSH; beta-endorphin; beta-LPH; beta-melanocyte-stimulating hormone; beta-MSH; corticotropin-like intermediary peptide; Corticotropin-lipotropin; gamma-LPH; gamma-MSH; lipotropin beta; lipotropin gamma; melanotropin alpha; melanotropin beta; melanotropin gamma; met-enkephalin; opiomelanocortin prepropeptide; OTTHUMP00000119991; OTTHUMP00000200964; POMC; Precursor of MSH; pro-ACTH-endorphin; Pro-opiomelanocortin; pro-opiomelanocortin-alpha; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); proopiomelanocortin preproprotein; proopiomelanocortin, beta (endorphin, beta); proopoimelanocortin, beta (endorphin, beta)

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Gene Aliases: ACTH; alpha-MSH; alphaMSH; BE; Beta-LPH; beta-MSH; CLIP; Gamma-LPH; gamma-MSH; LPH; MSH; NPP; POC; POMC; Pomc-1; Pomc1; Pomc2

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UniProt ID: (Human) P01189, (Mouse) P01193

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Entrez Gene ID: (Human) 5443, (Mouse) 18976, (Rat) 24664

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Function(s)
G-protein coupled receptor binding receptor binding hormone activity neuropeptide hormone activity type 3 melanocortin receptor binding type 4 melanocortin receptor binding type 1 melanocortin receptor binding molecular_function
Process(es)
generation of precursor metabolites and energy signal transduction neuropeptide signaling pathway cell-cell signaling regulation of blood pressure regulation of appetite negative regulation of tumor necrosis factor production cellular pigmentation glucose homeostasis positive regulation of transcription from RNA polymerase II promoter regulation of glycogen metabolic process regulation of corticosterone secretion feeding behavior peptide hormone processing
It has to be done as per old AB suggested Products section.
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