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  • Primary Antibodies ›
  • ABCG1 Antibodies

Invitrogen

ABCG1 Polyclonal Antibody

View all (16) ABCG1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ABCG1 Polyclonal Antibody

  • Antibody Testing Data (4)
ABCG1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ABCG1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 4

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ABCG1 Antibody (PA5-72939) in IHC (P)

Immunohistochemical analysis of ABCG1 in human lung, alveolar macrophages. Samples were incubated in ABCG1 polyclonal antibody (Product # PA5-72939). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ABCG1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ABCG1 Antibody in Western Blot (WB)
ABCG1 Antibody in Western Blot (WB)
ABCG1 Antibody in Flow Cytometry (Flow)
ABCG1 Polyclonal Antibody

Product Details

PA5-72939

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400
-

Flow Cytometry (Flow)

Assay-Dependent
-

In vitro Assay (IV)

Assay-Dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide made to an internal region of human ABCG1 (between residues 300-400).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2718793

Target Information

ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ABC transporter 8; ATP-binding cassette 8; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette, subfamily G, member 1; homolog of Drosophila white; MGC34313; White protein homolog; white protein homolog (ATP-binding cassette transporter 8)

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Gene Aliases: ABC8; ABCG1; AW413978; White; WHITE1; WHT1

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UniProt ID: (Human) P45844, (Mouse) Q64343

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Entrez Gene ID: (Human) 9619, (Mouse) 11307

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Function(s)
ATP binding phospholipid binding phospholipid transporter activity cholesterol binding cholesterol transporter activity toxin transporter activity sterol-transporting ATPase activity glycoprotein transporter activity protein homodimerization activity ADP binding protein heterodimerization activity protein dimerization activity nucleotide binding ATPase activity
Process(es)
regulation of transcription, DNA-templated cholesterol metabolic process detection of hormone stimulus response to organic substance negative regulation of macrophage derived foam cell differentiation regulation of cholesterol esterification positive regulation of cholesterol efflux negative regulation of cholesterol storage intracellular cholesterol transport cholesterol efflux phospholipid efflux response to lipid low-density lipoprotein particle remodeling high-density lipoprotein particle remodeling glycoprotein transport lipoprotein metabolic process cholesterol homeostasis amyloid precursor protein catabolic process reverse cholesterol transport positive regulation of cholesterol biosynthetic process transmembrane transport phospholipid homeostasis response to high density lipoprotein particle toxin transport transport lipid transport negative regulation of lipid storage cholesterol transport
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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