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Invitrogen
ABCA7 Monoclonal Antibody (7A1-144)
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FIGURE: 1 / 5
ABCA7 Antibody (MA5-24784) in WB
Product Details
MA5-24784
Species Reactivity
Host/Isotype
Class
Type
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Immunogen
Conjugate
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RRID
Target Information
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ABC 1 antibody; ABC Transporter 1; ABC1; ABC1 antibody; ATP-binding cassette sub-family A member 7; CERP; CERP antibody; EC 2.2.1.1; EC 3.6.3; EC 3.6.3.41; FLJ40025
Gene Aliases: Abc51; Abca7; ABCX
UniProt ID: (Mouse) Q91V24
Entrez Gene ID: (Mouse) 27403
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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