Invitrogen

2'-O-Methylguanosine Recombinant Rabbit Monoclonal Antibody (2J8L2)

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

MA5-42765

Applications
Tested Dilution
Publications

ELISA (ELISA)

1 µg/mL
-

Dot blot (DB)

1:500-1:2,000
-
Product Specifications

Species Reactivity

Chemical, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2J8L2

Immunogen

Chemical compounds corresponding to 2'-O-Methylguanosine(Gm).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911906

Product Specific Information

Immunogen sequence: Gm conjuga ted to KLH

Target Information

2'-O-Methylguanosine is derivative of the nucleoside residue cytidine with a methyl group attached to the 2'-oxygen position.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: 2'-O-Methylguanosine; casein kinase 1, alpha 1; casein kinase 1, alpha 1-like; casein kinase I alpha S-like; Casein kinase I isoform alpha; Casein kinase I isoform alpha-like; CASP-1; CASP1 nirs variant 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase-1; CK1; CKI-alpha; CKI-alpha-like; clock regulator kinase; down-regulated in lung cancer; epididymis secretory sperm binding protein Li 77p; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL-1BC; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; Methylguanosine; p45

View more View less

Gene Aliases: CASP1; CK1; CK1a; CKIa; CSNK1A1; CSNK1A1L; HEL-S-77p; HLCDGP1; ICE; IL1BC; IL1BCE; P45; PRO2975

View more View less

UniProt ID: (Human) P29466, (Human) P48729, (Human) Q8N752, (Mouse) P29452, (Rat) P97633

View more View less

Entrez Gene ID: (Human) 834, (Human) 1452, (Human) 122011, (Mouse) 12362, (Rat) 113927

View more View less

Function(s)
endopeptidase activity cysteine-type endopeptidase activity protein binding cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic process protein kinase activity protein serine/threonine kinase activity ATP binding kinase activity peptidase activity cysteine-type peptidase activity hydrolase activity scaffold protein binding magnesium ion binding glycoprotein binding peptide binding phosphoprotein binding
Process(es)
response to hypoxia proteolysis apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process signal transduction regulation of autophagy protein processing response to lipopolysaccharide interleukin-1 beta production response to ATP regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of interleukin-1 alpha secretion positive regulation of interleukin-1 beta secretion regulation of inflammatory response mitochondrial depolarization membrane hyperpolarization pyroptosis cellular response to mechanical stimulus cellular response to organic substance programmed necrotic cell death toxin transport cell morphogenesis protein phosphorylation phagocytosis mitotic nuclear division regulation of cell shape Wnt signaling pathway peptidyl-serine phosphorylation cell division Golgi organization cell surface receptor signaling pathway positive regulation of proteasomal ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process intermediate filament cytoskeleton organization negative regulation of canonical Wnt signaling pathway regulation of GTP binding beta-catenin destruction complex assembly beta-catenin destruction complex disassembly microglial cell activation myoblast fusion memory response to bacterium response to organic cyclic compound response to drug positive regulation of apoptotic process positive regulation of circadian sleep/wake cycle, non-REM sleep positive regulation of cytokine secretion
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support