proBDNF Antibodies

Antibodies that detect proBDNF can be used in several scientific applications, including Immunohistochemistry and Western Blot. These antibodies target proBDNF in Mouse, Human, Rat and Non-human primate samples. Our proBDNF polyclonal antibodies are developed in Rabbit, Sheep... Antibodies that detect proBDNF can be used in several scientific applications, including Immunohistochemistry and Western Blot. These antibodies target proBDNF in Mouse, Human, Rat and Non-human primate samples. Our proBDNF polyclonal antibodies are developed in Rabbit, Sheep and Guinea Pig. These antibodies have been verified by... Antibodies that detect proBDNF can be used in several scientific applications, including Immunohistochemistry and Western Blot. These antibodies target proBDNF in Mouse, Human, Rat and Non-human primate samples. Our proBDNF polyclonal antibodies are developed in Rabbit, Sheep and Guinea Pig. These antibodies have been verified by Relative expression to confirm specificity to proBDNF. Find the proBDNF antibody that fits your needs. Choose from 1 of 11 proBDNF antibodies, which have been validated in experiments with 15 publications and 22 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to... Antibodies that detect proBDNF can be used in several scientific applications, including Immunohistochemistry and Western Blot. These antibodies target proBDNF in Mouse, Human, Rat and Non-human primate samples. Our proBDNF polyclonal antibodies are developed in Rabbit, Sheep and Guinea Pig. These antibodies have been verified by Relative expression to confirm specificity to proBDNF. Find the proBDNF antibody that fits your needs. Choose from 1 of 11 proBDNF antibodies, which have been validated in experiments with 15 publications and 22 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. BDNF is synthesized as pre-proBDNF, followed by cleavage to proBDNF. Although further processing generates the mature, 14 kDa protein, pro-BDNF is biologically active and is secreted in synaptic vesicles along with the mature form. BDNF is widely expressed in the central nervous system and acts in an autocrine and paracrine manner on several classes of neurons. Signaling occurs mainly through the tyrosine kinase receptor TrkB, although binding to the lower-affinity receptor, p75-NTR, has also been demonstrated. BDNF promotes neuronal survival and differentiation and has been shown to play a critical role in memory formation and synaptic regulation. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimers and Huntington disease patients, and may also play a role in the regulation of stress response and in the biology of mood disorders.

Synonyms

abrineurin; ANON2; anorexia BDNF; Bdnf; BDNF precursor form; brain derived neurothrophic factor; brain derived neurotrophic factor; brain-derived neurotrophic factor; BULN2; neurotrophin; pro BDNF; ProBDNF

proBDNF Antibodies

Target Information

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